Meniscal Transplantation and its Effect on Osteoarthritis Risk
نویسندگان
چکیده
N. A. Smith, MSc, MRCS, Specialist Registrar, Trauma and Orthopaedics J. Achten, PhD, Senior Trial Manager N. Parsons, PhD, Statistician D. Wright, BSc (Hons), Senior Knee Physiotherapist B. Parkinson, FRACS (Orth), Consultant Orthopaedic Surgeon P. Thompson, FRCS (Orth), Consultant Orthopaedic Surgeon C. E. Hutchinson, MD, Professor of Imaging T. Spalding, FRCS (Orth), Consultant Orthopaedic Surgeon M. L. Costa, PhD, FRCS(Tr&Orth), Professor of Orthopaedic Surgery University of Warwick, Clifford Bridge Road, Coventry CV2 2DX, UK.
منابع مشابه
Meniscal Transplantation and its Effect on Osteoarthritis Risk: an abridged protocol for the MeTEOR study: a comprehensive cohort study incorporating a pilot randomised controlled trial.
OBJECTIVES Subtotal or total meniscectomy in the medial or lateral compartment of the knee results in a high risk of future osteoarthritis. Meniscal allograft transplantation has been performed for over thirty years with the scientifically plausible hypothesis that it functions in a similar way to a native meniscus. It is thought that a meniscal allograft transplant has a chondroprotective effe...
متن کاملIntra-articular Implantation of Mesenchymal Stem Cells, Part 2
Knee osteoarthritis (OA) after partial or total meniscectomy is a prevalent issue that patients must face. Various methods of replacing meniscal tissue have been studied to avoid this progression, including meniscal allograft transplantation, meniscal scaffolds, and synthetic meniscus replacement. Studies have shown that meniscal scaffolds may improve symptoms but have not been shown to prevent...
متن کاملMeniscal allograft transplantation: rationale for treatment.
The anatomy and microstructure of the menisci allow the effective distribution of load across the knee. Meniscectomy alters the biomechanical environment and is a potent risk factor for osteoarthritis. Despite a trend towards meniscus-preserving surgery, many tears are irreparable, and many repairs fail. Meniscal allograft transplantation has principally been carried out for pain in patients wh...
متن کاملMeniscal transplantation.
The aims of a meniscal replacement are: 1) to reduce the pain experienced by some patients following meniscus resection; 2) to prevent the degenerative changes of cartilage and the changes in subchondral bone following meniscus resection; 3) to avoid or reduce the risk of osteoarthritis following meniscus resection; 4) to restore optimally the mechanical properties of the knee joint after menis...
متن کاملClinical evaluation of arthroscopic-assisted allograft meniscal transplantation.
INTRODUCTION A meniscal deficient knee is at risk of early degenerative osteoarthritis. Allograft meniscal transplantation has been used to treat the meniscus deficiency to alleviate pain symptoms and to delay progression to arthritis. This case series aims to assess the postoperative outcomes of patients who have undergone meniscal allograft transplantation in our hospital. MATERIALS AND MET...
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